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Search Results for " polymorphonuclear leukocytes "

20

Compounds

Cat No. Product Name Synonyms Targets
T7739 L-Leucyl-L-Leucine methyl ester hydrochloride Leu-Leu-ome hydrochloride Others , Endogenous Metabolite
L-Leucyl-L-Leucine methyl ester hydrochloride (Leu-Leu-ome hydrochloride) is a lysosomal condensation product that cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes.
T27026 CJ-13,610 CJ 13610,CJ-13610 Lipoxygenase
CJ-13,610 is an orally active and nonredox-type inhibitor of 5-lipoxygenase (5-LOX). CJ-13,610 inhibits the biosynthesis of leukotriene B4 and regulates the expression of IL-6 mRNA in macrophages.
T22946 LY255283 LY 255283 Leukotriene Receptor
LY255283 is a specific antagonit of leukotriene B4 (LTB4) receptor. It inhibits the production of LTB(4) in human peripheral blood polymorphonuclear leukocytes (PMNL) and in monocytes activated by calcium ionophore A2318...
T68166 Traxanox Others
Traxanox is an orally available diuretic.Traxanox enhances phagocytosis of yeast granules by mouse peritoneal macrophages or rat peritoneal polymorphonuclear leukocytes in vitro.Restorative effect of Traxanox on inhibiti...
T36879L H-Leu-Leu-OMe . HBr H-Leu-Leu-OMe . HBr (16689-14-8 Free base) Others
H-Leu-Leu-OMe . HBr is a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes. H-Leu-Leu-OMe . HBr induces endolysosomal pathway stress and selectively eli...
T68166L Traxanox TFA Traxanox TFA(58712-69-9 Free base) Others
Traxanox TFA is an orally available diuretic. Traxanox TFA enhances phagocytosis of yeast granules by mouse peritoneal macrophages or rat peritoneal polymorphonuclear leukocytes in vitro. Traxanox TFA restores inhibition...
T4S1422 Praeruptorin E Others , Calcium Channel
1. Praeruptorin C and E can relax swine coronary artery and decrease contractility in guinea-pig left atria, these effects are similar in many respects to those displayed by drugs that have calcium entry blocking activit...
T69110 Aseanostatin P5
Aseanostatin P5 inhibits myeloperoxidase (MPO) release from human polymorphonuclear leukocytes.
T24305 L 651142 L651,142,L651142,L-651,142,L 651,142,L-651142
L 651142 is a weak inhibitor of the platelet-activating factor receptor. It is also binding to polymorphonuclear leukocytes.
T13716 (+)-Guaiacin Others
(+)-Guaiacin is a compound isolated from the bark of Machilus wangchiana Chun. It shows potent in vitro activities against the release of β-glucuronidase in rat polymorphonuclear leukocytes (PMNs) induced by platelet-act...
T15825 LY 178002 Retinoid Receptor
LY 178002 is an effective inhibitor of 5-lipoxygenase (5-LPO), phospholipase A2 (IC50: 0.6 μM for 5-lipoxygenase). LY 178002 also inhibits cellular production of LTB4 by human polymorphonuclear leukocytes and displays re...
TP2395 Nph-peptide
Nph-peptide can be used for photoaffinity labeling of the N-formyl peptide receptor site of intact human polymorphonuclear leukocytes.
T27408 Gea 3162 Gea3162,Gea-3162
Gea 3162 is a potent inhibitor of ADP-induced platelet aggregation in platelet rich plasma (PRP). GEA 3162 stimulates cGMP production in granulocytes, platelets, and polymorphonuclear leukocytes.
TN4486 Magnolianin Others
Magnolianin can inhibit strongly (IC50 = 0.45 uM) 5-HETE formation by die cytosol of guinea pig polymorphonuclear leukocytes.
T37460 Lipoxin B4 Lipoxin B4
Lipoxin B4 (LXB4) is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15(S)-HpETE by human leukocytes. At a concentration of 100 nM, LXB4 inhibits polymorphonuclear leukocyte (PMN) migration stimulate...
T21962 HZ52
HZ52 is a potent, reversible 5-lipoxygenase(5-LO) inhibitor. It blocks leukotriene(LTs) synthesis with an IC 50 of 0.7 μM in intact human polymorphonuclear leukocytes [1].
T38308 Lipoxin B4 methyl ester
Lipoxin B4 (LXB4) methyl ester is a lipid soluble prodrug form of the transcellular metabolite LXB4 . LXB4 is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15-HpETE by human leukocytes. At a concen...
T37649 5(S),12(S)-DiHETE
5(S),12(S)-DiHETE is a natural bioactive lipid derived from arachidonic acid . It is synthesized by glycogen-induced rabbit peritoneal polymorphonuclear leukocytes (PMNLs) incubated with AA. 5(S),12(S)-DiHETE can be prod...
T37382 1,2,3-Trieicosapentaenoyl-rac-glycerol
1,2,3-Trieicosapentaenoyl-rac-glycerol (EPA-TG) is a glycerol ester of eicosapentaenoic acid , which is an ω-3 fatty acid. An EPA-TG emulsion, administered i.v., lowers leukotriene B4 production by 40% in polymorphonucle...
T37975 13(S)-HODE-biotin
13(S)-HODE is the lipoxygenase metabolite of linoleic acid. 13(S)-HODE modulates the platelet-activating factor, leukotriene B4, and formyl-Met-Leu-Phe-induced calcium influx in human polymorphonuclear leukocytes. The me...
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