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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7739 | L-Leucyl-L-Leucine methyl ester hydrochloride | Leu-Leu-ome hydrochloride | Others , Endogenous Metabolite |
L-Leucyl-L-Leucine methyl ester hydrochloride (Leu-Leu-ome hydrochloride) is a lysosomal condensation product that cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes. | |||
T27026 | CJ-13,610 | CJ 13610,CJ-13610 | Lipoxygenase |
CJ-13,610 is an orally active and nonredox-type inhibitor of 5-lipoxygenase (5-LOX). CJ-13,610 inhibits the biosynthesis of leukotriene B4 and regulates the expression of IL-6 mRNA in macrophages. | |||
T22946 | LY255283 | LY 255283 | Leukotriene Receptor |
LY255283 is a specific antagonit of leukotriene B4 (LTB4) receptor. It inhibits the production of LTB(4) in human peripheral blood polymorphonuclear leukocytes (PMNL) and in monocytes activated by calcium ionophore A2318... | |||
T68166 | Traxanox | Others | |
Traxanox is an orally available diuretic.Traxanox enhances phagocytosis of yeast granules by mouse peritoneal macrophages or rat peritoneal polymorphonuclear leukocytes in vitro.Restorative effect of Traxanox on inhibiti... | |||
T36879L | H-Leu-Leu-OMe . HBr | H-Leu-Leu-OMe . HBr (16689-14-8 Free base) | Others |
H-Leu-Leu-OMe . HBr is a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes. H-Leu-Leu-OMe . HBr induces endolysosomal pathway stress and selectively eli... | |||
T68166L | Traxanox TFA | Traxanox TFA(58712-69-9 Free base) | Others |
Traxanox TFA is an orally available diuretic. Traxanox TFA enhances phagocytosis of yeast granules by mouse peritoneal macrophages or rat peritoneal polymorphonuclear leukocytes in vitro. Traxanox TFA restores inhibition... | |||
T4S1422 | Praeruptorin E | Others , Calcium Channel | |
1. Praeruptorin C and E can relax swine coronary artery and decrease contractility in guinea-pig left atria, these effects are similar in many respects to those displayed by drugs that have calcium entry blocking activit... | |||
T69110 | Aseanostatin P5 | ||
Aseanostatin P5 inhibits myeloperoxidase (MPO) release from human polymorphonuclear leukocytes. | |||
T24305 | L 651142 | L651,142,L651142,L-651,142,L 651,142,L-651142 | |
L 651142 is a weak inhibitor of the platelet-activating factor receptor. It is also binding to polymorphonuclear leukocytes. | |||
T13716 | (+)-Guaiacin | Others | |
(+)-Guaiacin is a compound isolated from the bark of Machilus wangchiana Chun. It shows potent in vitro activities against the release of β-glucuronidase in rat polymorphonuclear leukocytes (PMNs) induced by platelet-act... | |||
T15825 | LY 178002 | Retinoid Receptor | |
LY 178002 is an effective inhibitor of 5-lipoxygenase (5-LPO), phospholipase A2 (IC50: 0.6 μM for 5-lipoxygenase). LY 178002 also inhibits cellular production of LTB4 by human polymorphonuclear leukocytes and displays re... | |||
TP2395 | Nph-peptide | ||
Nph-peptide can be used for photoaffinity labeling of the N-formyl peptide receptor site of intact human polymorphonuclear leukocytes. | |||
T27408 | Gea 3162 | Gea3162,Gea-3162 | |
Gea 3162 is a potent inhibitor of ADP-induced platelet aggregation in platelet rich plasma (PRP). GEA 3162 stimulates cGMP production in granulocytes, platelets, and polymorphonuclear leukocytes. | |||
TN4486 | Magnolianin | Others | |
Magnolianin can inhibit strongly (IC50 = 0.45 uM) 5-HETE formation by die cytosol of guinea pig polymorphonuclear leukocytes. | |||
T37460 | Lipoxin B4 | Lipoxin B4 | |
Lipoxin B4 (LXB4) is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15(S)-HpETE by human leukocytes. At a concentration of 100 nM, LXB4 inhibits polymorphonuclear leukocyte (PMN) migration stimulate... | |||
T21962 | HZ52 | ||
HZ52 is a potent, reversible 5-lipoxygenase(5-LO) inhibitor. It blocks leukotriene(LTs) synthesis with an IC 50 of 0.7 μM in intact human polymorphonuclear leukocytes [1]. | |||
T38308 | Lipoxin B4 methyl ester | ||
Lipoxin B4 (LXB4) methyl ester is a lipid soluble prodrug form of the transcellular metabolite LXB4 . LXB4 is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15-HpETE by human leukocytes. At a concen... | |||
T37649 | 5(S),12(S)-DiHETE | ||
5(S),12(S)-DiHETE is a natural bioactive lipid derived from arachidonic acid . It is synthesized by glycogen-induced rabbit peritoneal polymorphonuclear leukocytes (PMNLs) incubated with AA. 5(S),12(S)-DiHETE can be prod... | |||
T37382 | 1,2,3-Trieicosapentaenoyl-rac-glycerol | ||
1,2,3-Trieicosapentaenoyl-rac-glycerol (EPA-TG) is a glycerol ester of eicosapentaenoic acid , which is an ω-3 fatty acid. An EPA-TG emulsion, administered i.v., lowers leukotriene B4 production by 40% in polymorphonucle... | |||
T37975 | 13(S)-HODE-biotin | ||
13(S)-HODE is the lipoxygenase metabolite of linoleic acid. 13(S)-HODE modulates the platelet-activating factor, leukotriene B4, and formyl-Met-Leu-Phe-induced calcium influx in human polymorphonuclear leukocytes. The me... |